Synchrotron radiation in radiology: novel X-ray sources

X-rays, the key ingredient of radiology, are still primarily produced with the mechanism discovered by Röntgen over one century ago. A different approach, however, is becoming increasingly important: the use of synchrotron sources based on fast-moving electrons and on their relativistic properties. We discuss the elements of this new strategy, its practical implementation, and some new types of synchrotron sources under development. The present and potential impact on radiology of different classes of synchrotron sources is briefly and realistically analyze

Spontaneous bilateral subdural haematomas in the posterior cranial fossa revealed by MRI

A 52-year-old woman treated for acute myeloproliferative disease developed progressive stupor. CT showed obstructive hydrocephalus resulting from unexplained mass effect on the fourth ventricle. MRI revealed bilateral extra-axial collections in the posterior cranial fossa, giving high signal on T1- and T2-weighted images, suggesting subacute subdural haematomas. Subdural haematomas can be suspected on CT when there is unexplained mass effect. MRI may be essential to confirm the diagnosis and plan appropriate treatmen

Multiple Networks for Interhemispheric Integration in the Visual Brain: fMRI BOLD Response Increases with EEG Synchronization

2006.05.6-12, ISMRM 2006, International Society for Magnetic Resonance in Medicine, 14th Scientific Meeting, Seattle, Washington, USA. Book of abstracts ELECTRONIC POSTER DISCUSSION: The Future of BOLD? Resting State Signals and Multiple Modalities: Electronic Poste

Connecting biodiversity monitoring with soil inventory information - A Swiss case study

Switzerland is one of the first countries in the world to monitor its biological diversity. The Federal Office for the environment (FOEN), triggered by the Rio world summit, initiated 1995 a program for this purpose called Biodiversity Monitoring in Switzerland (BDM). According to the Convention on Biological Diversity various biodiversity targets were defined and the action plan strategy biodiversity Switzerland serves to implement these strategic goals. Unfortunately, up to very recently, soil was not part of these considerations. In the Swiss biodiversity monitoring system a core indicator, species diversity in habitats, is designed to document changes in species diversity of vascular plants and mosses in Switzerland’s major habitats. Together with the current land use and general metadata like elevation, slope, exposition and geology these data are stored in a central database. Since 2001 the totally 1’600 sites based on a regular grid (6 by 4 km) are resampled in a 5 years interval. In the third sampling campaign (2011-2015) the setting was broadened by taking soil samples at all locations possible. At each site 4 replicates 0-20 cm were taken to provide predictions on plot scale variability. All samples were prepared in the laboratory of the Swiss Soil Monitoring Network. Exploratory data analyses for pH, soil organic carbon and nitrogen revealed distinct patterns according to land use as well as to altitude; pH decreases from colline to alpine zones. Furthermore, regional analyses show enormous differences between the northern and southern side of the Alps. Connecting measured soil parameters with the outcome of the BDM survey enables to determine the impact of environmental conditions on species diversity of vascular plants and mosses as well as on soil-plant interactions. Therefore, connecting measured soil inventory data and plant and moss diversity information provide a clear added value to the Biodiversity Monitoring in Switzerland

fMRI responses in medial frontal cortex that depend on the temporal frequency of visual input.

Functional networks in the human brain have been investigated using electrophysiological methods (EEG/MEG, LFP, and MUA) and steady-state paradigms that apply periodic luminance or contrast modulation to drive cortical networks. We have used this approach with fMRI to characterize a cortical network driven by a checkerboard reversing at a fixed frequency. We found that the fMRI signals in voxels located in occipital cortex were increased by checkerboard reversal at frequencies ranging from 3 to 14 Hz. In contrast, the response of a cluster of voxels centered on basal medial frontal cortex depended strongly on the reversal frequency, consistently exhibiting a peak in the response for specific reversal frequencies between 3 and 5 Hz in each subject. The fMRI signals at the frontal voxels were positively correlated indicating a homogeneous cluster. Some of the occipital voxels were positively correlated to the frontal voxels apparently forming a large-scale functional network. Other occipital voxels were negatively correlated to the frontal voxels, suggesting a functionally distinct network. The results provide preliminary fMRI evidence that during visual stimulation, input frequency can be varied to engage different functional networks

Spurious signals in DQF spectroscopy: two-shot stimulated echoes

The most widely used technique for double-quantum filtered (DQF) single-voxel spectroscopy (SVS) is based on a symmetric PRESS sequence with two additional spatially unselective π/2 pulses, one of which is usually frequency selective. The actual filtering, rejecting signals from all uncoupled resonances, can be done by suitable phase cycling of the rf pulses in successive shots, but in practice gradient filtering is always used. Under usual conditions the sequence repetition time is comparable to the spin-lattice relaxation time, and a stimulated echo is formed by five out of the ten rf pulses in two consecutive shots. This echo is not filtered out by the gradients, and additional phase cycling is needed to eliminate it. Its spatial origin is the full transverse slice selected by the last pulse of the PRESS sequence. The SVS shimming procedure may create an important field variation in this slice (outside the volume of interest VOI). Water singlet signals therefore appear in a band of frequencies other than 4.7 ppm, and remain unaffected by water suppression pulses. In practice phase-alternation schemes can reduce these spurious signals by several orders of magnitude, but even then they may mask the weak metabolite signals of interest. We describe a strategy to minimize these spurious signals and propose a 16-step phase cycling scheme that attenuates the stimulated echo in every two-step subcycl